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Master Syllabus

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Administrative Unit: Physical and Biological Sciences Department
Course Prefix and Number: CHEM 312L
Course Title: Organic Chemistry II Laboratory
Number of:
Credit Hours 2
Lecture Hours 0
Lab Hours 3
Catalog Description:

Laboratory experiences to complement CHEM 312 focusing on synthetic methods. Students majoring in Chemistry must earn a grade of C or higher. $30 lab fee. Prerequisites: CHEM 312 or concurrent enrollment; CHEM 310L with a grade of C or higher.

Prerequisite(s) / Corequisite(s):

CHEM 312 or concurrent enrollment; CHEM 310L with a grade of C or higher.

Course Rotation for Day Program: Offered Spring.
Text(s): Most current editions of the following:

Microscale and Miniscale Organic Chemistry Laboratory Experiment
By Schoffstall, Gaddis, Druelinger (McGraw-Hill)
Small Scale Syntheses: A Laboratory Textbook of Organic Chemistry
By Zanger and McKee (McGraw-Hill)
Experiments and Techniques in Organic Chemistry
By Pasto, Johnson, and Miller (Prentice Hall)
Course Objectives
  • To implement standard rules and practices of laboratory safety.
  • To acquire facility with laboratory equipment used in organic chemistry.
  • To use the scientific method to design and conduct experiments.
  • To perform and evaluate experiments using a variety of chemical reactions.
  • To use critical analysis skills to interpret data and draw conclusions.
  • To develop skills in keeping a lab notebook and writing scientific reports.
    Measurable Learning
  • Locate and use MSDS sheets for specific chemical substances; use MSDS to determine molecular formula, hazards, physical properties, exposure limit, personal protective equipment, first aid, and disposal procedures.
  • Accomplish experimental manipulations using lab equipment such as melting point apparatus, UV-VIS spectrophotometer, FT-IR spectrophotometer, NMR spectrophotometer .
  • Identify unknowns based on spectroscopic properties.
  • Perform and evaluate experiments in nucleophilic substitution, electrophilic aromatic substitutions, Diels-Alder reactions, Grignard reactions, Wittig reactions, and esterifications.
  • Utilize organometallic intermediates; synthesize organometallic compounds.
  • Perform solvolysis of an alkyl halide; describe the reaction kinetics.
  • Design and analyze experiments using the scientific method.
  • Write clear, concise, and accurate scientific laboratory reports.
    Topical Outline:
  • Safety rules
  • Solvolysis of an alkyl halide
  • Grignard reaction
  • Preparation of an ester
  • Preparation of ferrocene and acetylferrocene
  • Solubility
  • Carbohydrates
  • Electrophilic aromatic substitution
    Culminating Experience Statement:

    Material from this course may be tested on the Major Field Test (MFT) administered during the Culminating Experience course for the degree. 
    During this course the ETS Proficiency Profile may be administered.  This 40-minute standardized test measures learning in general education courses.  The results of the tests are used by faculty to improve the general education curriculum at the College.


    Recommended maximum class size for this course: 22

    Library Resources:

    Online databases are available at You may access them from off-campus using your CougarTrack login and password when prompted.

    Prepared by: Julie Estabrooks Date: November 20, 2009
    NOTE: The intention of this master course syllabus is to provide an outline of the contents of this course, as specified by the faculty of Columbia College, regardless of who teaches the course, when it is taught, or where it is taught. Faculty members teaching this course for Columbia College are expected to facilitate learning pursuant to the course objectives and cover the subjects listed in the topical outline. However, instructors are also encouraged to cover additional topics of interest so long as those topics are relevant to the course's subject. The master syllabus is, therefore, prescriptive in nature but also allows for a diversity of individual approaches to course material.

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