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Master Syllabus

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Administrative Unit: Physical and Biological Sciences Department
Course Prefix and Number: BIOL 342L
Course Title: Genetics Laboratory
Number of:
Credit Hours 2
Lecture Hours 0
Lab Hours 2
Catalog Description:

Laboratory experiences to complement BIOL 342; methodology and applications in classical and molecular genetics. $40 lab fee. Students majoring in Biology must earn a grade of C or higher. Prerequisites: BIOL 110L with a grade of C or higher; BIOL 290L; BIOL 342 or concurrent enrollment.

Prerequisite(s) / Corequisite(s): BIOL 110L with a grade of C or higher; BIOL 290L; BIOL 342 or concurrent enrollment.
Course Rotation for Day Program: Offered Spring.
Text(s): Most current editions of the following:

Textbooks listed are not necessarily the textbook(s) used in the course.

Genetics Laboratory Investigations
By Mertens & Hammersmith (Prentice Hall)
Contemporary Genetics Laboratory Manual
By Scott (Morton Publishing Co.)
Genetics Laboratory Manual
By Adamkewics (Wiley & Sons)
A Classroom Guide to Yeast Experiments: A Research Approach to Mendelian and Molecular Genetics and Genetic-Environmental Interactions
By Manney (Carolina Biological)
Course Objectives
  • To use the scientific method to design and conduct experiments.
  • To use critical analysis skills to interpret data and draw conclusions.
  • To perform and evaluate methods in classical genetic analysis using bacterial, plant, animal and fungal organisms.
  • To employ and evaluate methods in molecular genetics.
    Measurable Learning
  • Perform and analyze monohybrid and dihybrid crosses using experimental organisms.
  • Describe and appropriately use probability and Chi-square analysis.
  • Outline the events of mitosis and meiosis.
  • Demonstrate differences and similarities in meiosis of plants and animals.
  • Isolate DNA.
  • Use appropriate laboratory methods and equipment for genetic studies.
  • Discriminate between single gene and polygenic inheritance.
  • Apply principles of population genetics.
    Topical Outline:
  • Monohybrid and dihybrid crosses
  • Genotypic and phenotypic ratios
  • Probability and Chi-square analysis
  • Cell reproduction: mitosis and meiosis
  • Linkage, crossing over, chromosome mapping
  • Mutation and complementation
  • Human genetics, pedigrees and polygenic inheritance
  • DNA isolation, purification and restriction enzyme mapping
  • Gene expression and protein synthesis in bacteria and yeast cells
    Culminating Experience Statement:

    Material from this course may be tested on the Major Field Test (MFT) administered during the Culminating Experience course for the degree. 
    During this course the ETS Proficiency Profile may be administered.  This 40-minute standardized test measures learning in general education courses.  The results of the tests are used by faculty to improve the general education curriculum at the College.


    Recommended maximum class size for this course: 25

    Library Resources:

    Online databases are available at You may access them from off-campus using your CougarTrack login and password when prompted.

    Prepared by: Julie Estabrooks Date: October 9, 2008
    NOTE: The intention of this master course syllabus is to provide an outline of the contents of this course, as specified by the faculty of Columbia College, regardless of who teaches the course, when it is taught, or where it is taught. Faculty members teaching this course for Columbia College are expected to facilitate learning pursuant to the course objectives and cover the subjects listed in the topical outline. However, instructors are also encouraged to cover additional topics of interest so long as those topics are relevant to the course's subject. The master syllabus is, therefore, prescriptive in nature but also allows for a diversity of individual approaches to course material.

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