Theoretical foundations of basic cell biology, including structure, function, and synthesis of the plasma membrane and subcellular organelles; cell adhesion and the extracellular matrix; cell transport, communication, division, cancer and programmed cell death. Prerequisite: BIOL 112; CHEM 109 or CHEM 110. Concurrent enrollment in BIOL 290L is strongly recommended.
Prerequisite(s) / Corequisite(s):
BIOL 112; CHEM 109 or CHEM 110. Concurrent enrollment in BIOL 290L is strongly recommended.
Course Rotation for Day Program:
Most current editions of the following:
Texts addressing molecular aspects of cell biology are suitable, such as:
Molecular Biology of the Cell
By Alberts, et al. (Garland) Recommended
Molecular Cell Biology
By Lodish, et al. (W.H. Freeman) Recommended
The Cell: A Molecular Approach
By Cooper (ASM Press) Recommended
Course Learning Outcomes
Examine fundamental principles that characterize cellular organization and function.
Understand the composition of biological membranes, and relate structure to membrane function.
Understand the mechanisms of the cell cycle regulation.
Examine the function of the various subcellular organelles.
Understand the mechanisms of signaling pathways.
Describe the composition, structure, and function of the extracellular matrix and basal lamina.
Major Topics/Skills to be Covered:
Structure of biological membranes
Transport across biological membranes
Protein sorting into subcellular organelles and vesicular transport
Cell cycle control
Cell-to-cell adhesion and the extracellular matrix
Chemical signaling between cells
Recommended maximum class size for this course: 30
NOTE: The intention of this master course syllabus is to provide an outline of the contents of this course, as specified by
the faculty of Columbia College, regardless of who teaches the course, when it is taught, or where it is taught. Faculty members teaching this
course for Columbia College are expected to facilitate learning pursuant to the course learning outcomes and cover the subjects listed in the Major Topics/Skills to be Covered section.
However, instructors are also encouraged to cover additional topics of interest so long as those topics are relevant to the course's
subject. The master syllabus is, therefore, prescriptive in nature but also allows for a diversity of individual approaches to course material.