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Master Syllabus

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Administrative Unit: Physical and Biological Sciences Department
Course Prefix and Number: CHEM 420
Course Title: *Biochemistry I
Number of:
Credit Hours 3
Lecture Hours 3
Lab Hours 0
Catalog Description:

The first of a two semester course that will outline the structure, function, and chemical properties of biological molecules. Topics will include protein function, enzyme kinetics, bioenergetics, membrane transport, cell signalling pathways, DNA information technology, and central intermediate metabolism. Student majoring in Biology or Chemistry must earn a grade of C or higher. Cross-listed as BIOL 420. Prerequisites BIOL 290 and CHEM 310. CHEM 312 is strongly encouraged.

Prerequisite(s) / Corequisite(s):

Prerequisites BIOL 290 and CHEM 310. CHEM 312 is strongly encouraged.

Course Rotation for Day Program:

Offered Fall. 

Text(s): Most current editions of the following:

Lehninger Principles of Biochemistry
By Nelson, David M. & Michael M. Cox (Freeman)
Fundamental of Biochemistry: Life at the Molecular Level
By Voet, Donald, Judith G. Voet & Charlotte W. Pratt (Wiley)
By Berg, Jeremy M. & Tymoczko, John L. & Stryer, Lubert (Freeman)
Course Learning Outcomes
  1. Understand the structure and function of basic biomolecules in the cell as well as the macromolecules they form.
  2. Understand the role buffering plays in chemical reactions of the cell.
  3. Understand protein-substrate interactions and how to characterize these interactions.
  4. Understand enzyme function and activity and characterize the type of enzyme by  use  of kinetics.
  5. Understand the dynamic role biological membranes play in transport and investigate their coordination in biosignalling pathways.
  6. Examine the catabolic and anabolic reactions of central intermediate metabolism and apply these principles to the understanding of cellular status.
Major Topics/Skills to be Covered:

o Water, pH, and buffers

  • Amino acids, peptides, and proteins

  • Protein structure and function

  • Enzymes

  • Glycobiology

  • Nucleotides, nucleic acids, and DNA information technologies

  • Lipids, biological membranes, transport, and biosignaling

  • Bioenergetics and biochemical reaction types

  • Central Intermediate Metabolism: Glycolysis, gluconeogenesis, pentose phosphate pathway, and the citric acid cycle.



    Recommended maximum class size for this course: 25

    Library Resources:

    Online databases are available at the Columbia College Stafford Library.  You may access them using your CougarTrack login and password when prompted.

    Prepared by: Kent Strodtman Date: October 31, 2016
    NOTE: The intention of this master course syllabus is to provide an outline of the contents of this course, as specified by the faculty of Columbia College, regardless of who teaches the course, when it is taught, or where it is taught. Faculty members teaching this course for Columbia College are expected to facilitate learning pursuant to the course learning outcomes and cover the subjects listed in the Major Topics/Skills to be Covered section. However, instructors are also encouraged to cover additional topics of interest so long as those topics are relevant to the course's subject. The master syllabus is, therefore, prescriptive in nature but also allows for a diversity of individual approaches to course material.

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